Глава 5

1. A. Pentland, «How Big Data Can Transform Society for the Better,» Scientific American, October 1, 2014, http://www.scientificamerican.com/article/how-big-data-can-transform-society-for-the-better/.

2. S. Lohr, "Sizing Up Big Data, Broadening Beyond the Internet," New York Times, June 19, 2013, http://bits.blogs.nytimes.com/2013/06/19/sizing-up-big-data-broadening-beyond-the-internet/.

3. "Epidemiolog y," Wikipedia, accessed August 13, 2014, 2014, http://en.wikipedia.org/wiki/Epidemiology.

4. J. L. Gardy et al., "Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak," The New England Journal of Medicine 364 (2011): 730–739.

5. E. Topol, "Individualized Medicine from Prewomb to Tomb," Cell 157 (2014): 241–253.

6. T. Simonite, "Life's Trajectory Seen Through Facebook Data," MIT Technology Review, April 24, 2013, http://www.technologyreview.com/view/514186/lifes-trajectory-seen-through-facebook-data/.

7. A. Regalado, "Stephen Wolfram on Personal Analytics," MIT Technology Review, May 8, 2013, http://www.technologyreview.com/news/514356/stephen-wolfram-on-personal-analytics/.

8. N. A. Christakis and J. H. Fowler, Connected (New York, NY: Little, Brown and Co., 2009).

9. "Phenotype," Wikipedia, accessed August 13, 2014, http://en.wikipedia.org/wiki/Phenotype.

10. "Microphones as Sensors: Teaching Old Microphones New Tricks," The Economist, June 1, 2013, http://www.economist.com/news/technology-quarterly/21578518-sensor-technology-microphones-are-designed-capture-sound-they-turn-out.

11. G. Slabodkin, "Study: iPhone App for Speech Laterality Just as Reliable as Lab Brain Tests,"FierceMobileHealthcare, February 12, 2013, http://www.fiercemobilehealthcare.com/story/study-iphone-app-speech-laterality-just-reliable-lab-brain-tests/2013-02-12.

12. I. Ezkurdia et al., "Multiple Evidence Strands Suggest That There May Be as Few as 19,000 Human Protein-Coding Genes," Human Molecular Genetics, June 16, 2014, http://www.ncbi.nlm.nih.gov/pubmed/24939910.

13. A. Butte, "Should Healthy People Have Their Genomes Sequenced at This Time?" Wall Street Journal, February 15, 2013, http://online.wsj.com/news/articles/SB1000087 2396390443884104577645783975993656.

14. E. C. Hayden, "Non-Invasive Method Devised to Sequence DNA of Human Eggs," Nature News & Comment, December 19, 2013, http://www.nature.com/news/non-invasive-method-devised-to-sequence-dna-of-human-eggs-1.14412.

15. R. W. Taylor et al., "Use of Whole-Exome Sequencing to Determine the Genetic Basis of Multiple Mitochondrial Respiratory Chain Complex Deficiencies," Journal of the American Medical Association 312, no. 1 (2014): 68–77.

16. J. Lupski, "Genetics. Genome Mosaicism– One Human, Multiple Genomes," Science 341 (2013): 358–359.

17. M. J. McConnell et al., "Mosaic Copy Number Variation in Human Neurons," Science 342 (2013): 632.

18. I. Cho and M. Blaser, "The Human Microbiome: At the Interface of Health and Disease," Nature Reviews Genetics 13 (2012): 260–270.

19. R. Chen et al., "Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes," Cell 148 (2012): 1293–1307.

20. E. Aiden and J.-B. Michel, "The Predictive Power of Big Data," Newsweek, December 25, 2013, http://www.newsweek.com/predictive-power-big-data-225125.

21. R. Almeling, "The Unregulated Sperm Industry," New York Times, December 1, 2013, http://www.nytimes.com/2013/12/01/opinion/sunday/the-unregulated-sperm-industry.html.

22. M. Allyse and M. Michie, "You Can't Predict Destiny by Designing Your Baby's Genome," Wall Street Journal, November 8, 2013, http://online.wsj.com/news/articles/SB10001424 052702304448204579182353852538422.

23. G. Naik, "'Designer Babies:' Patented Process Could Lead to Selection of Genes for Specific Traits," Wall Street Journal, October 3, 2013, http://online.wsj.com/article/SB10001424052 702303492504579113293429460678.html.

24. S. Morain, M. Greene, and M. Mello, "A New Era of Noninvasive Prenatal Testing," New England Journal of Medicine 369 (2013): 499–501.

25. A. Agarwal et al., "Commercial Landscape of Noninvasive Prenatal Testing in the United States," Prenatal Diagnosis 33 (2013): 521–531.

26. Illumina, "Verinata Health's verifi® Prenatal Test Available Through the California Prenatal Screening Program," Illumina Investor Relations News Release, November 1, 2013, http://investor.illumina.com/phoenix.zhtml?c=121127&p=irol-newsArticle&ID=1871236&highlight=.

27. A. Schaffer, "Too Much Information," MIT Technology Review, December 17, 2013, http://www.technologyreview.com/review/522661/too-much-information/.

28. A. D. Marcus, "Genetic Testing Leaves More Patients Living in Limbo," Wall Street Journal, November 20, 2013, http://online.wsj.com/news/articles/SB100014240 52702303755504579206000052566432.

29. B. Wilcken, "Newborn Screening: Gaps in the Evidence," Science 342 (2013): 197–198.

30. E. Gabler, "Delays at Hospitals Across the Country Undermine Newborn Screening Programs, Putting Babies at Risk of Disability and Death," Journal Sentinel, November 16, 2013, http://www.jsonline.com/watchdog/watchdogreports/Deadly-Delays-Watchdog-Report-Delays-at-hospitals-across-the-country-undermine-newborn-screening-programs-putting-babies-at-risk-of-disability-and-death-228832111.html.

31. R. Greenfield, "Tracked Since Birth: The Rise of Extreme Baby Monitoring," Fast Company, November 15, 2013, http://www.fastcompany.com/3021601/innovation-agents/tracked-since-birth-the-pros-and-cons-of-extreme-baby-monitoring.

32. D. Epstein, The Sports Gene (New York, NY: Penguin, 2013), 256.

33. W. Koh et al., "Noninvasive In Vivo Monitoring of Tissue-Specific Global Gene Expression in Humans," PNAS Early Edition, May 2, 2014, http://www.pnas.org/content/early/2014/05/02/1405528111.

34. A. R. McLean, "Coming to an Airport Near You," Science 342 (2013): 1330–1331.

35. M. R. Wilson et al., "Actionable Diagnosis of Neuroleptospirosis by Next-Generation Sequencing," New England Journal of Medicine, June 19, 2014, http://www.nejm.org/doi/full/10.1056/NEJMoa1401268.

36. J. N. Weinstein et al., "The Cancer Genome Atlas Pan-Cancer Analysis Project," Nature Genetics 45, no. 10 (2013): 1113–1120.

37. G. Frampton et al., "Development and Validation of a Clinical Cancer Genomic Profiling Test Based on Massively Parallel DNA Sequencing," Nature Biotechnology 31 (2013): 1023–1031.

38. J. Couzin-Frankel, "Cancer Immunotherapy," Science 342 (2013): 1432–1433.

39. A. L. Williams et al., "Sequence Variants in SLC16A11 Are a Common Risk Factor for Type 2 Diabetes in Mexico," Nature 506 (2014): 97–101.

40. J. C. Florez et al., "Association of a Low-Frequency Variant in HNF1A With Type 2 Diabetes in a Latino Population," Journal of the American Medical Association 311, no. 22 (2014): 2305–2314.

41. I. Moltke et al., "A Common Greenlandic TBC1D4 Variant Confers Muscle Insulin Resistance and Type 2 Diabetes," Nature, June 18, 2014, http://www.nature.com/nature/journal/ vaop/ncurrent/full/nature13425.html.

42. A. R. Harper and E. J. Topol, "Pharmacogenomics in Clinical Practice and Drug Development," Nature Biotechnology 30, no. 11 (2012): 1117–1124.

43. C.-H. Chen et al., "Variant GADL1 and Response to Lithium Therapy in Bipolar I Disorder," New England Journal of Medicine 370 (2013): 119–128.

44. A. B. Jorgensen et al., "Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease," New England Journal of Medicine, July 3, 2014, http://www.nejm.org/doi/full/10.1056/NEJMoa1308027.

45. A. K. Pandey et al., "Functionally Enigmatic Genes: A Case Study of the Brain Ignorome," PLoSOne 9, no. 2 (2014): 1–11.

46. M. M. Newman, "Sudden Cardiac Arrest: A Healthcare Crisis," Sudden Cardiac Arrest Foundation, 2013, accessed August 18, 2014 http://www.sca-aware.org/about-sca.

Похожие книги из библиотеки